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Clinical, demographic, and cerebrospinal fluid (CSF) measurements from subjects participating in a clinical study investigating whether biological measurements in CSF can be used to diagnose or predict Alzheimer's disease.

Usage

ad_data

Format

ad_data

A list containing:

diagnosis

An R factor vector containing the Alzheimer's disease diagnosis for 333 subjects.

predictors

A data frame containing demographic and laboratory measurements for the study subjects, including the Genotype variable.

The Genotype predictor records the subject's Apolipoprotein E (APOE) genotype. APOE has three variants (E2, E3, and E4), with six possible genotype combinations formed by inheriting one variant from each parent. APOE genotype is associated with Alzheimer's disease risk.

These data are a modified version of the values used in the original publication.

Source

Craig-Schapiro, R., Kuhn, M., Xiong, C., Pickering, E. H., Liu, J., Misko, T. P., Perrin, R. J., et al. (2011). Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis. PLoS ONE, 6(4), e18850.